干扰素联合炎琥宁治疗手足口病患儿临床疗效和安全性

Clinical Efficacy and Safety of Interferon Joint Yanhuning Injection in Treatment of Children with Hand,Foot and Mouth Disease

目的：探讨干扰素联合炎琥宁治疗手足口病患儿临床疗效和安全性。方法：运用随机数字表法将2011年8月～2012年8月在我院儿科收治的118例手足口病患儿分为两组,即A组和B组,A组患儿给予干扰素治疗,而B组患儿加用炎琥宁治疗,两组患儿其他治疗措施完全相同。比较两组患儿的临床疗效和安全性。结果：B组患儿治疗总有效率（96.61%）明显高于A组患儿的（86.44%）,有显著性差异（P〈0.05）,B组患儿不良反应无明显增加,无显著性差异（P〉0.05）。结论：干扰素联合炎琥宁治疗小儿手足口病疗效肯定,优于单用干扰素,具有安全可靠和不良反应少等特点。

Objective：To investigate the treatment of interferon combined with Yanhuning child patients with HFMD clinical efficacy and safety. Methods： Use the random number table, from August 2011 to August 2012 at the pediatric hospital treated 118 cases of hand, foot and mouth disease children are divided into two groups, Group A and Group B, A group of children given interferon treatment, group B the children plus Yanhuning treatment, two groups of children with other therapeutic measures are identical. Compared between the two groups of children with clinical efficacy and safety. Results：Treatment of B-group children total efficiency （96.61%） was significantly higher than the children of the group A （86.44%）, a significant difference （P〈0.05）, no significant increase in the adverse reactions of the B group of children, no significant difference （P〉0.05）.Conclusion：Unterferon the joint Yanhuning treatment of children with hand, foot and mouth disease is effective and better than the single-interferon has a safe, reliable and fewer adverse reactions.