酒石酸托特罗定治疗输尿管结石术后留置双J管患者下尿路症状效果评价

Clinical efficacy of Tolterodine tartrate for LUTS after ureteral calculi surgery with double-J

目的探讨酒石酸托特罗定治疗输尿管结石术后留置双J管患者下尿路症状的临床效果。方法选择2012年6月～2013年2月在我院进行治疗的输尿管结石患者40例为研究对象。所有患者均采用输尿管镜碎石取石术，术后患侧留置相同的双J管。随机分为两组。研究组20例，术后给予酒石酸托特罗定口服，对照组作为空白对照．不进行任何处理。比较两组下尿路症状情况。结果干预后，研究组尿频、尿急、夜尿、储尿期症状评分、IPSS总分、qol较干预前显著下降，差异有统计学意义（P〈0.05或P〈0.01）。干预后两组之间以上各指标比较，差异有显著统计学意义（P〈0.05或P〈0.01）。结论酒石酸托特罗定能够显著改善输尿管结石术后留置双J管患者下尿路的症状，值得临床推广使用。

Objective To discuss clinical efficacy of Toherodine tartrate for LUTS after ureteral calculi surgery with double-J. Methods Selected 40 cases with ureteral calculus who were treated by ureteral calculi surgery with double- J were selected into study group and control group. Study was treated by Tolterodine tartrate after operation,and control group as blank control. LUTS of two groups were compared. Results Frequent micturition, urgent urination, enuresis nocturna, urine storage period symptom scores, IPSS, qol of study after treatment were lower than before treatment （P〈0.05 or P〈0.01）. And the index above of study group were lower than control group after treatment （P〈0.05 or P〈0.01）. Conclusion Toherodine tartrate can improve LUTS after ureteral calculi surgery with double -J , worthy of clinical usage.