间苯三酚辅助欣普贝生引产效果分析

The effect of dinoprostone and phloroglucinol in delivery

目的:探讨欣普贝生联合间苯三酚针对缓解过频过长宫缩及对促进产程进展的效果。方法:随机将使用欣普贝生促宫颈成熟治疗期间出现宫缩的200位孕妇分为2组。研究组:欣普贝生促宫颈成熟治疗在出现宫缩后予静脉注射间苯三酚针80mg;对照组不使用间苯三酚。观察2组宫缩情况、潜伏期时间、胎心变化、剖宫产率、产后出血量、新生儿评分等。结果:研究组对欣普贝生引起的过频过长宫缩缓解率达96.8%,潜伏期时间明显低于对照组,剖宫产率明显低于对照组(P<0.05);产后出血量、新生儿评分差异无统计学意义(P>0.05)。结论:间苯三酚能有效缓解欣普贝生引起的异常宫缩,延长欣普贝生使用时间,增加促宫颈成熟的作用,对缩短产程、提高阴道分娩率有意义。

[ Objective] To explore the effect of dinoprostone and phloroglucinol in relieving overfrequency and excess uterine contraction and promote labor program. [ Method] 200 pregnant women who had uterine contraction after using dinoprostone were divided into 2 groups randomly. Experiment group was treated by phloroglucinol injection （80mg） after uterine contrac- tion, while control group was not treated. Uterine contraction, eclipse period, fetal heart change, rote of C- sect, postpartum hemorrhage, APGAR score were observed. [ Result ] In experiment group, the rote of relieving uterine contraction was 96. 8 %, eclipse period and rate of C - sect were lower than those of control group. There were no significant differences about postpamun hemorrhage and A_PGAR score. [ Conclusion] Phloroglucinol could relieve abnormal uterine contraction caused by dinoprostone, prolong using time of dinoproston and increase the effect of promoting cervix maturate. Phlomglucinol may decur- tare labor and raise rate of vaginal delivery.