二根龙蛭汤对短暂性脑缺血发作患者认知功能障碍的影响

Impact of Ergenlongzhi Decoction on Transient Ischemic Attack in Patients with Cognitive Dysfunction Treatment

目的观察二根龙蛭汤对短暂性脑缺血发作(TIA)患者认知功能障碍的影响。方法将112例符合诊断标准的TIA患者随机分为基础组、对照组和治疗组,分别采用吡拉西坦片、吡拉西坦片+复方丹参片、吡拉西坦片+二根龙蛭汤进行治疗,治疗前和治疗30 d后采用蒙特利尔认知评估量表(MoCA量表)对认知功能进行评估,评估结果对比分析。结果治疗组脱落病例5例,对照组脱落病例3例,基础组脱落病例4例。治疗组治疗前后比较,CoMA评分明显提高(P<0.05),治疗组较对照组及基础组CoMA评分提高(P<0.05)。结论二根龙蛭汤用于对TIA患者的治疗,治疗后CoMA评分明显提高,认知功能明显改善,值得临床推广应用。

Objective： To observe the impact of Ergenlongzhi Decoction on ischemic attack in patients with cognitive dysfunction treatment.Methods： 112 patients were randomly divided into the basis group with piracetam tablet,the control group with piracetam tablet and compound salvia tablets and the treatment group with piracetam and Ergenlongzhi Decoction.After 30 d,the cognitive functions were analysised with MoCA among these groups.Results： There were 5 patients missed in the treatment group,3 patients missed in the control group and 4 patients missed in the basis group.In the treatment group,the cognitive function and MoCA of patients after treatment were better significantly than those before treatment.Meanwhile,the CoMA scores in the treatment group were higher remarkably than those in the other groups（all P 0.05）.Conclusion： It is better that the cognitive function and MoCA of patients with TIA treated with Ergenlongzhi Decoction.