艾司西酞普兰联合认知行为治疗对抑郁焦虑共病患者的疗效

Effects of escitalopram combined with cognitive therapy in treatment of depression and anxiety

目的:评价艾司西酞普兰联合认知行为治疗对抑郁焦虑共病患者的治疗效果。方法:将符合ICD-10诊断标准的62例抑郁焦虑共病患者随机分为研究组和对照组各31例,研究组给予艾司西酞普兰合并认知行为治疗,对照组单予艾司西酞普兰治疗。疗程8周。应用临床疗效标准及汉密尔顿抑郁量表(HAMD)、汉密尔顿焦虑量表(HAMA)定期评定疗效,不良反应量表(TESS)评定安全性。结果:在治疗第1、2、4、8周末,研究组疗效优于对照组,具有显著性统计学意义(P<0.01)。结论:艾司西酞普兰联合认知行为治疗对抑郁焦虑共病患者效果优于单用艾司西酞普兰。

Objective ： To determine the efficacy of escitalopram combined with cognitive behavior therapy for treating the depression and anxiety. Methods ： Sixty - two patients with depression and anxiety who met ICD - 10 criteria of depression and anxiety were randomly divided into the treatment group （ treated with escitalopram in addition to cognitive behavior therapy ） and the control group （ only with escitalopram）. All the patients in the two groups received the treatment for 8 weeks. The therapeutic effects were assessed by Hamilton Depression Rating Scale （ HAMD ） , HAMA and treatment emergent symptom scale （ TESS ）. Results ： At the 1 st, 2nd,4tb and 8th weekend, the effects in the treatmnt group were better than those in the control group, respectively （ P 〈 0.01 ）. Conclusions：Escitalopram combined with cognitive behavior therapy is more satisfactoy than escitalopram in depression and anxiety.