经尿道激光气化术治疗浅表性膀胱癌的疗效观察及安全性评估

Efficacy and safety of transurethral laser vaporization in treating superficial bladder cancer

目的观察经尿道激光汽化术治疗浅表性膀胱癌的疗效及安全性。方法选择在我院就诊的浅表性膀胱癌患者120例作为研究对象,随机分为观察组和对照组,观察组给予经尿道激光气化术治疗,对照组采用经尿道膀胱肿瘤电切术治疗,观察2组手术相关指标、应激指标以及远期预后情况。结果观察组平均手术时间[(72.21±8.42)min]、术中出血量[(43.73±4.79)mL]、术后引流量[(11.93±1.43)mL]、术后卧床上时间[(1.87±0.23)d]、血糖水平[(4.28±0.44)mmol/L]、HAMA评分(15.41±1.76)、HAMD评分(13.41±1.46)、NRS评分(2.29±0.36)、以及复发率[8.33%(5/60)]均明显低于对照组;胰岛素水平[(13.31±1.56)U/mL]、生活质量评分85.12±8.91、KPS评分86.84±9.34明显高于对照组。结论经尿道膀胱肿瘤激光气化术能够减小手术创伤、缓解术后应激、改善远期预后,具有积极的临床价值。

ObjectiveTo study the efficacy and safety of transurethral laser vaporization in treating superficial bladder cancer. Methods A total of 120 cases of superficial bladder cancer patients were randomly divided into the observation group treated with transurethral laser vaporization and the control group treated with transurethral resection of bladder tumor （TURBT）. The operation index, stress index and longterm prognosis were observed. Results In the observation group, the operation time was （72.21±8.42） min, bleeding volume was （43.73±4.79）mL, postoperative drainage volume was （11.93±1.43）mL, postoperative bed time was （187±0.23）d, BG level was （4.28±0.44）mmol/L, HAMA score was 15.41±1.76,HAMD score was 13.41±1.46, NRS score was 2.29±0.36, and the recurrence rate was 8.33% （5/60）. All these indexes were significantly lower than those in the control group; Ins level was （13.31±1.56） U/mL, quality of life score was 85.12±8.91, KPS score was 86.84±9.34, which were higher than those in the control group. ConclusionsTransurethral laser vaporization is clinically significant because it can reduce the operation wound, relieve stress, and improve longterm prognosi