小儿急性病毒性脑炎的视觉通路受累(英文)

Visual pathways involvement in children with acute viral encephalitis

目的：探讨急性病毒性脑炎患儿的视觉通路受累程度和性质。方法：对30例急性病毒性脑炎患者（年龄5～12岁）,疾病最初显现的12d内视觉诱发电位（VEP）进行调查。在急性病毒性脑炎患者和水痘蜱传脑炎患者之间比较P100峰潜伏期及振幅。结果：两种形式脑炎患儿之间无显着差异。研究对象组中,40%的患者表现出视觉皮层功能障碍（P100振幅降低）,沿视觉通路（P100潜伏期延长）电导率温和放缓的迹象。结论：研究发现,视觉通路对病毒性脑炎有很强的耐受性。功能性视皮层对该疾病的抵抗力低。

AIM： To investigate pathways involvement encephalitis extent and nature of visual n children with acute viral METHODS： Thirty patients （age 5-12 years） viral encephalitis underwent visual evoked （VEP） investigation within 12 days from the of the first signs of disease. Latency and ampl with acute potentials appearance itude of P100peak were compared with normative data and between patients with varicella and tick-borne encephalitis. RESULTS： There were no significant differences between children with these two forms of encephalitis. In the whole group in 40% of the cases signs of the visual cortex dysfunction （P100 amplitude lowering） and mild slowing of the conductivity along the visual pathways （Plee latency lengthening） were seen. In 3% of the cases retrobulbar optic neuritis was diagnosed. CONCLUSION-The results indicate that visual pathway have good endurance to the viral encephalitis anatomically, but functionally visual cortex is quite vulnerable towards general disturbances caused by this kind of illness.