SMILE与飞秒激光制瓣LASIK治疗近视的疗效对比

Comparison of small incision lenticule extraction and femtosecond laser assisted LASIK for myopia

目的:比较VisuMax飞秒激光角膜基质透镜切除术(small incision lenticule extraction,SMILE)与飞秒激光制瓣的准分子激光原位角膜磨镶术(femtosecond laser assisted LASIK,FEMTO LASIK)治疗近视的临床效果。方法:该研究纳入的近视及近视散光患者中,42例83眼接受了VisuMax飞秒激光SMILE手术,47例94眼接受了非球面切削的FEMTO LASIK。通过手术前及手术后1d;1wk;1,3mo的检查结果评价两种手术的安全性、有效性、预测性、稳定性及其不良事件。结果:术后3mo,平均安全性指数SMILE组为1.10±0.16,FEMTO LASIK组为1.09±0.16;平均有效性指数两组分别为1.10±0.16,1.08±0.12。术后3mo时等效球镜值在±1.00D范围内者两组分别为82眼(98.8%)和91眼(96.8%);±0.50D范围内者两组分别为73眼(88.0%)和78眼(83.0%)。术后3mo时等效球镜分别为0.11±0.23,0.08±0.25D。两组均无明显并发症。结论:VisuMax飞秒激光角膜基质透镜取出术与飞秒激光制瓣的非球面切削LASIK治疗近视同样安全有效、有很好的可预测性和稳定性。

AIM- To compare the postoperative visual outcomes of VisuMax small incision lenticule extraction （SMILE） and femtosecond laser assisted LASIK （FEMTO LASIK） for myopia. METHODS ; Eighty-tree eyes （ 42 patients） underwent VisuMax SMILE and 94 eyes （47 patients） received FEMTO LASIK to correct myopia were comprised. The safety, efficacy, predictability, stability and adverse events were assessed preoperatively and l d, 1 week, 1 month, 3 months postoperatively, RESULTS ; At 3 months, the mean safety index was 1.10± 0.16 in the SMILE group and 1.09±0. 16 in the FEMTO LASIK group; the mean efficacy index was respectively 1.10±0.16 and 1.08±0.12; Spherical equivalent （SE） was respectively 0.11 ±0.23D and 0. 08±0. 25D within ± 1.00D of the targeted SE correction in 82 eyes （98. 8%） of the SMILE group and 91 eyes 96.8%） of the FEMTO LASIK group and SE within ＋0.50D in 73 eyes （88.0%） of the SMILE group and 78 eyes （83.0%） of the FEMTO LASIK group. There were no significant complications in both groups. CONCLUSION; SMILE and FEMTO LASIK have equal safety, efficacy, predictabilityand stability in the treatment of myopia.