聚乳酸防粘连膜植入联合小梁切除术治疗原发性闭角型青光眼

Effect of polylactic acid membrane implantation combined with trabeculectony on primary angle-closed glaucoma

目的:探讨聚乳酸防粘连膜植入联合小梁切除术治疗原发性闭角型青光眼的疗效。方法:闭角型青光眼患者41例47眼随机分为试验组(聚乳酸防粘连膜植入联合小梁切除术)和对照组(单纯小梁切除术)。术后随访6mo,观察两组患者术后视力、眼压、滤过泡、前房等情况,并进行比较分析。结果:术后6mo试验组视力不同程度提高,眼压明显降低,和对照组比较,差异有统计学意义(P<0.05);试验组88.0%的患者形成功能性滤过泡,显著高于对照组(59.1%),差异有统计学意义(P<0.05)。结论:聚乳酸防粘连膜植入联合小梁切除术治疗原发性闭角型青光眼简单、安全、有效。

AIM： To evaluate the effect of polylactic acid membrane （PLA） implantation combined with trabeculectony on primary angle-closed glaucoma. METHODS： Totally, 41 patients（47 eyes） with primary angle-closed glaucoma were randomly divided into 2 groups. PLA implantation combined with trabeculectony was performed for the experimental group while trabeculectony for the control group. Cases were followed up for 6 months postoperatively, with observation and comparative analysis on visual acuity （VA）, intraocular pressure （lOP）, filtering bleb and anterior chamber depth. RESULTS： In the experimental group,6 months after the surgery, VA was improved to different degrees and lOP reduced greatly. According to comparison between the two groups, the differences were of statistic significance （P〈 0. 05）. The rate of functional filtering bleb in the experimental group （88.0%） was much higher than that of the control group （59.1%, P〈0.05）. CONCLUSION： PLA implantation combined with trabeculectomy for the treatment of primary angle-closed glaucoma is simple, safe and effective.