带角膜缘干细胞的自体结膜瓣移植术治疗复发性翼状胬肉

Autologous conjunctiva transplantation with stem cells on edge of cornea for recurrent pterygium

目的：观察带角膜缘干细胞的自体结膜瓣移植术治疗复发性翼状胬肉的临床有效性和实用性。方法：复发性翼状胬肉患者53例57眼。复发性翼状胬肉切除全部病灶组织后移植带角膜缘干细胞的自体结膜瓣,移植结膜瓣取自术眼上方结膜。结果：术眼57眼术后随访1～12mo,3例出现复发,复发率5%。1例发生角巩膜自溶,并手术治疗。余53眼经1～12mo的随访角膜创面愈合良好,植片全部存活,无明显手术痕迹,治愈率93%。结论：采用自体角膜缘干细胞移植术治疗复发性翼状胬肉,手术取材方便、创面修复快,术后复发率低,满足部分患者美观需求,改善了术后效果,是一种理想的术式,值得基层临床推广应用。

AIM： To observe the clinical effectiveness and practicality the autologous conjunctiva transplantation with stem cells on edge of cornea for recurrent pterygium. METHODS： Of the 53 recurrent pterygium patients （57 eyes）, after all pathological tissues were removed, underwent the autologous conjunctiva transplantation with stem cells on edge of cornea which were locked above conjunctival transplantation of the operated eye. RESULTS： Postopretive follow-up was 1-12 months for all 57 eyes, of which 3 eyes （5%） relapsed. The corneoscleral autolysis was occurred in one eye and surgery treatment was conducted. Corneal wounds were healing and transplantations survived well for the remaining 53 patients without obvious surgical marks. Cure rate was 93%. CONCLUSION： Autologous conjunctiva transplantation with stem cells on edge of cornea for recurrent pterygium can meet the aesthetic requirements of the some patients, with the advantages of obtaining material easily, faster wound healing, lower postoperative recurrence rate, meeting the aesthetic needs of some patients and improving postoperative results. Thus, it is an ideal surgery and is worthy of applying on primary hospital.