加味大承气汤联合针刺治疗胃癌术后胃瘫综合征32例临床观察

Efficacy of Supplemented Major Qi-Coordinating Decoction Combined with Acupuncture on Postsurgical Gastroparesis Syndrome: A Clinical Observation of 32 Cases

目的:观察加味大承气汤联合针刺治疗胃癌术后胃瘫综合征的临床疗效。方法:将64例胃癌术后胃瘫综合征患者随机分为对照组和治疗组各32例。两组均给予胃肠减压、抗感染、维持水电解质平衡及营养支持等常规治疗,对照组胃管注入西沙比利联合静脉滴注红霉素治疗,治疗组给予胃管注入加味大承气汤联合针刺足三里、合谷、内关、中脘、脾俞、胃俞等穴位治疗,两组治疗4周后观察胃瘫减轻时间和中医症状积分改善情况,并评价两组临床疗效。结果:与对照组比较,治疗组胃瘫恢复时间明显缩短,临床疗效和中医症状积分改善均优于对照组,差异有统计学意义(P<0.05)。结论:以加味大承气汤联合针刺治疗胃癌术后胃瘫综合征具有明显的临床疗效。

Objective： To observe the effect of Supplemented Major Qi-Coordinating Decoction combined with acupuncturc on postsurgical gastroparesis syndrome （PGS）. Methods： 64 PGS patients were randomly divided into the treatment and control group, 32 cases in each group. Patients in two groups were given gastrointestinal decompression, anti-infection, maintain water electrolyte balance and nutritional support on the basis of conventional therapy; patients were given intragastric administration of cisapride combined with intravenous infusion of erythromycin in control group and Supplemented Major Qi-Coordinating De- coction combined with acupuncture at ZuSanLi, HeGu, NeiGuan, ZhongWan, PiShu, WeiShu eta!, in treatment group. Gastro- paresis reducing time, TCM symptoms integral and clinical curative effect were observed in 4 weeks. Results： Comparing with the control group, the gastroparesis recovery time was significantly shorter in treatment group; and the clinical curative effect and TCM symptom scores in treatment group were better than that of control group, the difference was statistically significant （P〈0.05）. Conclusion： Supplemented Major Qi-Coordinating Decoction combined with acupuncture can provide obvious clinical effect on PGS.