前列腺穿刺活检患者膀胱内前列腺突入长度差异的临床意义

Significance of difference in length of intravesical prostate protrusion in predicting diagnosis of patients undergoing prostate biopsy

目的探讨前列腺癌(PCa)和前列腺增生(BPH)患者膀胱内前列腺突入(IPP)长度差异对前列腺穿刺活检诊断的价值。方法 71例前列腺穿刺活检患者,均在经直肠超声(TRUS)引导下行自动活检枪前列腺穿刺活检,并经病理证实;同时测量IPP长度和前列腺体积(PV)。比较PCa组(22例)和BPH组(49例)IPP差异,分析IPP在不同截点水平诊断PCa的敏感度和特异度。结果 71例患者的IPP长度均值为(9.3±7.3)mm,PCa组为(6.6±5.0)mm,明显短于BPH组的(11.5±8.4)mm(P<0.05);IPP长度和PV呈显著正相关(r=0.691,P<0.05)。取IPP长度7.5mm作为截点值时,其判断PCa的特异度与灵敏度均为66.7%。结论 IPP是判断前列腺穿刺活检患者是否患PCa的一个有意义的指标;在IPP≤7.5mm的前列腺穿刺患者中,PCa检出率较高。

Objective To investigate the significance of the difference in length of intravesical prostate protrusion （IPP） in predicting diagnosis of patients undergoing prostate needle biopsy. Methods Prostate biopsy was performed in 71 patients, in whom the measurements of the length of IPP and prostate volume（PV） by transrectal uhrasonography（TRUS） were carried out. The patients were divided into prostatic cancer（group PCa, 22 cases） and benign prostatic hyperplasia（group BPH, 49 cases） according to pathological diagnosis. The sensitivity and specificity rates of the length difference of IPP in PCa diagnosis were evaluated. Reasuls The length of IPP was （9.3＋7.3） mm in avalage in 71 patients,which was shorter in group PCa than that in group BPH[（6. 6＋5. 0） mm vs. （11.5t：8. 4） mm] （P〈0. 05）. The length of IPP was positively correlated to the PV（r=0. 691, P〈0. 05）. Taking 7.5 mm as the cut-off point of IPP length, the sensitivity and specificity rates for the diagnosis of PCa were 66.7% and 66.7%. Conclusion The length of IPP is a valuable parameter to diagnose PCa in patients undergoing prostate needle biospsy. The patients with a length of IPP shorter than 7.5 ram were with a higher detection rate of PCa.