肢端色痣357例分析

Analysis of Acral Nevi in 357 Cases

目的探讨肢端色痣的临床及病理学特征，并评估手术治疗的效果。方法对2000年10月-2010年10月本科确诊的357例肢端色痣患者的f临床与病理资料进行回顾性分析。结果357例患者中，交界痣192例，复合痣79例，蓝痣32例，皮内痣27例，雀斑样痣27例。皮损多数为圆形或椭圆形，直径0．1—2．5cm，以1．0cm居多，呈淡棕或灰黑色，部分表面有毛发，少数表面破渍、出血或颜色加深。术后随访满意率随时间延伸而逐渐提高。典型的痣细胞呈卵圆形或立方形，细胞质轮廓清楚。细胞核大，呈圆形或椭圆形。结论交界痣占有较高比例，其中皮内痣和混合痣及雀斑样痣无1例发生于手背，蓝痣多发生于手背。手术切除在肢端色痣治疗中效果满意，肢端色痣手术切除皮损送病理检查有助于确定其病理类型及是否完全切除．且疗效满意。

Objective To investigate the clinical and pathological features of acral nevi, and to assess the efficacy of surgical treatment. Results Clinical and pathological data were retrospectively analyzed in 357 patients with acral nevi confirmed by our department from October 2000 - October 2010. Results Among 357 cases, 192 eases were junctional nevi, 79 cases were compound nevi, 32 cases were blue nevi, 27 eases were intrader- real nevi, and 27 cases were lentigos. Most of lesions appeared round or oval in the diameter of 0.1 - 2.5cm with the majority of 1.0era. The color ranged from light brown to grey black. Other features included hairy, erosion, bleeding and hyperpigmentation. The longer the post-operative follow-up, the higher satisfaction rate was. Typica] nevus cells were oval or cubic with large round or oval nuclei. Conclusion Most nevi are junctional nevi. No compound nevus, intradcrmal nevus and lentigo occur on the dorsal hands. Blue nevi often occur on the dorsal hands. Surgical remove of acral nevi is an effective regime. Pathological examination could determine the type of nevus and whether the nevi are completely removed.