组织学改变在BPH并发急性尿潴留患者中的作用分析

Histological changes of the prostate and acute urinary retention in patients with benign prostatic hyperplasia

目的:探讨前列腺梗死、前列腺组织学炎症、前列腺增生类型在良性前列腺增生(BPH)并发急性尿潴留(AUR)中的关系。方法:回顾性分析我院初诊BPH合并AUR与无AUR患者共102例,其中AUR组49例,无AUR组53例。比较两组之间前列腺梗死、前列腺组织学炎症、前列腺增生类型发生率。同时比较两组间年龄、国际前列腺症状评分(IPSS)、前列腺特异性抗原(PSA)、前列腺总体积(PV)。结果:AUR组血PSA较无AUR组明显升高[(8.2±4.6)μg/L vs(4.3±5.5)μg/L,P<0.05),两组患者年龄、IPSS、PV比较差异无统计学意义(P均>0.05)。前列腺增生类型与AUR无相关性(P>0.05),前列腺梗死和前列腺组织学炎症可增加BPH患者AUR发生机率,存在前列腺梗死的BPH患者发生AUR的概率是无前列腺梗死者的5.620倍(P<0.05),存在前列腺组织学炎症的BPH患者发生AUR的概率是无炎症者的2.362倍(P<0.05)。结论:前列腺梗死和前列腺组织学炎症可能是BPH患者发生AUR的危险因素。

Objective： To investigate the roles of prostatic infarction, prostatic inflammation and the type of prostatic hypetpla- sia in acute urinary retention （AUR） in patients with benign prostatic hyperplasia （BPH）. Methods： We retrospectively analyzed 102 cases of BPH, 49 complicated by AUR and the other 53 without AUR. We compared the incidences of prostatic infarction and prostatic inflammation, the types of prostatic hyperplasia, the patients＇age, the level of prostate specific antigen （PSA）, the prostate volume, and international prostate symptom score （IPSS） between the AUR and non-AUR groups. Results： The PSA level was sig- nificantly increased in the AUR group as compared with the non-AUR group （ P 〈 0.05 ）. There were no statistically significant differ- ences between the two groups in the mean age, prostate volume and IPSS （ P 〉 0.05 ）. The type of prostatic hyperplasia showed no cor- relation with AUR. The incidence rate of AUR was 5. 620 and 2. 326 times higher in the BPH patients with prostatic infarction and prostatic inflammation respectively than in those without （ P 〈 0.05 ）. Conclusion ： Prostatic infarction and prostatic inflammation areimportant risk factors of AUR in BPH patients.