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周围型肺癌超声造影表现与微血管密度的相关性研究 被引量:7

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摘要 目的探讨周围型肺癌超声造影表现与肿瘤微血管密度(MVD)的关系。方法40例经超声引导下穿刺活检确诊的周围型肺癌(腺癌22例,鳞癌18例),穿刺前行超声造影检查,穿刺后行常规病理检查及CD34免疫组织化学染色并计算MVD。用时间强度曲线分析腺癌和鳞癌的峰值强度及增强强度指数,计算强度参数与MVD的相关性。结果腺癌的MVD(28.5±6.2)、造影峰值强度(69.5±13.6)及强度指数(5.1±1.6)均高于鳞癌(分别为23.8±8.4、53.4±15.2及4.0±1.3,均P<0.05)。肺腺癌超声造影峰值强度及强度指数与其MVD呈正相关(r分别为0.654及0.776);肺鳞癌峰值强度及强度指数与其MVD呈正相关(r分别为0.811及0.878)。结论超声造影可以动态评价周围型肺癌血管灌注状况。
出处 《天津医药》 CAS 北大核心 2013年第10期1008-1009,共2页 Tianjin Medical Journal
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