摘要
沙门菌是一类胞内侵袭性兼性厌氧菌，减毒后仍保留其抗原性，现在广泛作为DNA疫苗的载体。沙门菌携带相关抗原基因对多种肿瘤有显著的抑制效果，而且携带修复基因对放化疗后的机体损伤有着明确的修复作用。
Salmonella is a kind of intracellular invasive facultative anaerobe, maintaining its antigenici- ty after being attenuated. Now, it has been widely used as a transporter of DNA vaccines. Salmonella carrying related antigen gene can inhibit multiple tumors, and salmonella carrying repair gene has a clear repair effect for the organism injury after chemoradiotherapy.
出处
《国际肿瘤学杂志》
CAS
2013年第10期748-751,共4页
Journal of International Oncology
基金
国家自然科学基金（81071839）
关键词
减毒沙门菌
肿瘤
疫苗载体
损伤修复
Attenuated salmonella
Neoplasms
Vaccine carrier
Damage repairment
