白蔹化学成分研究

Chemical Constituents from Ampelopsis japonica

目的：研究白蔹的化学成分。方法：利用正反相硅胶、凝胶（Sephadex LH-20）等多种柱色谱法对白蔹化学成分进行分离纯化,并根据理化性质和波谱数据进行结构鉴定。结果：分离得到15个化合物,分别鉴定为羽扇豆醇（1）,β-谷甾醇（2）,大黄素甲醚（3）,β-谷甾醇亚油酸酯（4）,丹皮酚（5）,4-p-樟烷-1,8-二醇（6）,香草醛（7）,α-生育酚（8）,α-生育醌（9）,α-甲基吡咯酮（10）,botcinins D（11）,5α,8α-过氧化麦角甾-6,22-二烯-3β-醇（12）,4-酮松脂醇（13）,bungein A（14）,lasiodiplodin（15）。结论：化合物4~15均为首次从该植物中分离得到。

Objective： To investigate the chemical constituents of Ampelopsis japonica.Method： Multichromatographic methods including Silica gel column chromatography and Sephadex LH-20 gel column chromatography were employed for the isolation and purification.The structures were identified on the basis of chemical evidence and spectral data.Result： Fifteen compounds were isolated and identified as lupeol（1）,βsitosterol（2）,physeion（3）,β-sitosterol linoleate（4）,paeonol（5）,4-p-menthane-1,8-diol（6）,vanillin（7）,α-tocopherol（8）,α-tocopheryl quinone（9）,α-methyl-pyrrole-ketone（10）,botcinins D（11）,5α,8αepidioxyergosta-6,22-dien-3β-ol（12）,4-keto pinoresinol（13）,bungein A（14）,lasiodiplodin（15）.Conclusion： Compounds 4-15 are obtained from this plant for the first time.