剖宫产围术期预防使用抗茵药物情况分析

Analysis of prophylactic use of antimicrobial drugs during peri-operative period of cesarean

目的研究剖宫产围术期预防性应用抗菌药物的用药疗程与效果的关系。方法对莱芜市妇幼保健院2012年1月至2012年8月收治的187例剖宫产手术患者进行分组，试验组95例，对照组92例。对两组产妇不同给药时间的平均住院日、术后体温恢复到37．5℃以下的时间、切口感染、恶露和再次入院等情况进行比较分析。结果试验组与对照组比较，术后感染率和术后体温恢复到37．5℃以下的时间比较差异无统计学意义（P〉0．05）。两组产妇均未发生切口感染，无一例出现恶露异味。结论剖宫产围术期预防性应用抗茵药物于断脐后立即快速静脉滴注即可达到预防感染的效果，无特殊情况一般不必追加用药次数。

Objective To study the relationship between the medication regimens of prophylactic use of antimicrobial drugs and effect during perioperative period of cesarean. Methods One hundred and eighty-seven cases of cesarean section patients, from January 2012 to August 2012, were divided into test group （95 cases） and control group （92 cases）. The average length of hospital stay, the time of postopera-tive temperature down below 37.5℃, incision infection, the lochia and readmission between the two groups were compared. Restflts There were no significantly differences in postoperative infection rates and the time of postoperative temperature down below 37.5 ℃ between the two groups （P 〉 0. 05 ）. Neither groups occurred wound infection, and there was no ease of lochia smell. Conclusions Prophylactic use of antimicrobial drugs during peri-operative period of cesarean should be used by intravenous infusion when umbilical cord is cut, which can prevent infection. There was no need to append additional medication, without special circumstances.