临床药师在剖宫产围术期合理使用抗菌药物的作用

Role of Clinical Pharmacist in Rational Use of Antibiotics in Perioperative Cesarean Section

目的了解产科剖宫产围术期预防用抗菌药物的情况，对比分析t临床药师对产科合理使用抗茵药物的干预作用。方法收集临床药师参与前2012年1～3月手术病历130份，参与后2012年4月--6月手术病历142份，分析用药合理性。结果临床药师参与产科剖宫产围术期预防用抗菌药物使用后，其选药、用药时机、用法、剂量、用药方式趋于合理，用药时间大幅缩短。结论临床药师实施合理用药干预措施有效、可行，但仍存在选药不当、用药疗程偏长等问题；参与围术期预防用抗茵药物的监督作用仍需加强。

OBJECTIVE To understand the obstetric cesarean section perioperative use antimicrobial drugs to prevent, compari- son and analysis of the clinical pharmacists in clinical rational use of antimicrobial agents intervention role. METHODS There are 130 medical records of patients with cesarean section before intervention were collected from our hospital Jan-Mar. in 2012 and 142 medical records of patients after intervention in Apr-Jun. were collected. The rationality of antibiotics was analyzed. RESULTS Com- pared with the before intervention rationality of perioperative antibiotics prophylaxis in the intervention group were significantly in- creased and irrationality were significantly decreased. The average duration of antibiotic prophylaxis in the intervention group was signifi- cantly shorter than before intervention. CONCLUSION The rational use of drugs in the implementation of clinical pharmacists inter- vention measures is effective and feasible. Some problems should be further standardized, such as irrational selection of antibiotics and prolonged application.