AlPW_(12)O_(40)/TiO_2催化苯甲醚乙酰化反应

Acylation reaction of anisole catalyzed by AlPW_(12)O_(40)/TiO_2

以钛酸丁酯、磷钨酸、硝酸铝为主要原料,采用溶胶-凝胶法制备了AlPW12O40/TiO2复合催化剂。考察了对苯甲醚乙酰化反应制备对甲氧基苯乙酮的催化活性。实验结果表明:AlPW12O40负载量、催化剂用量、反应物配比、反应时间及反应温度等是影响催化效果的重要因素。反应的适宜条件为:AlPW12O40负载量为35%,乙酸酐与苯甲醚物质的量之比为2.5,催化剂用量为反应物总质量的3%,反应温度100℃,反应60 min,苯甲醚转化率可达到84.5%。催化剂易于分离,重复使用仍有较高催化活性。

Composite acid catalyst, aluminum dodecatungsto- phosphate supported by titanium dioxide （A1PWI20,o/TiO2 ） was prepared via sol-gel method. The catalytic activity to the acetylate reaction of anisole was investigated. The results show that AlPW12O40/TiO2 catalyst keeps the primary Keggin structure and is an effective catalyst for Friedel-Crafts acylation reaction. The conversion ratio of anisole is 84.5%.