参麦注射液在特殊人群(儿童)中应用的文献分析

Literature review of application of Shenmai injection in special populations(children)

该文以维普资讯数据库和中国知网为资料来源,采用文献计量分析法,对参麦注射液在儿科临床应用的特点进行了分析和归纳。结果表明,虽然参麦注射液说明书中无儿童用药相关说明,但在儿科临床应用广泛,可治疗小儿病毒性心肌炎、肺炎、新生儿缺血缺氧性脑病、新生儿硬肿症、腹泻等多种疾病,取得了较好疗效。但用药中存在用量用法、疗程、溶媒不统一,且有药物热、皮疹、脸红、胸闷等不良反应发生,故建议采取有效措施加强儿童用药规范,减少用药风险,提高临床治疗水平。

Objective： Analyze the characteristic features of Shenmai injections as used in pediatric clinics, to improve the specifications for use in children in order to decrease risks. Method： We preformed statistical analyses on data from the CNKI and VIP databases relevant to the clinical application af Shenmai injections in children. Pediatric indications, usage and dosage, length of treat- ment, solubility of the drugs in mediums and adverse reactions were summarized. Result： Shenmai injection is widely used in clinical pediatrics, and is reported to show effectivenss for conditions such as viral myocarditis, pneumonia, neonatal hypoxic ischemic enceph- alopathy, neonatal scleroderma, diarrhea and other diseases. However, there are no specific specifications regarding usage and dosa- ges, length of treatments, or instructions regarding solvents. Adverse reactions reported include, drug rash, heat, blushing, and chest tightness amongst others. Conclusion： Effective measures should be adopted to standardize the clinical regulations regarding Shenmai injections for use in children, to reduce risks, and thereby raise clinical treatment standards.