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尿酸对多巴胺能神经元保护作用的研究进展 被引量：3

Progress in the Effects of Uric Acid to Dopaminergic Neurons
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摘要 氧化应激因素是帕金森病发病的重要机制之一.越来越多的研究证实高水平的尿酸可以降低帕金森病的发病风险,尿酸水平会影响帕金森病的进程.尿酸对多巴胺能神经元具有一定的保护作用. Parkinson＇ s disease （PD） is a retrogressive disease of central nervous system. Its characteristic includes the degeneration and loss of dopaminergic neurons in the midbrain. The morbidity of PD is 1.7% in the elderly （ 〉 65 years） in China. The pathogenic mechanism of PD is unclear. Now many studies show that uric acid may reduce the dangerous of the morbidity of PD.
作者 巩利 张琪林 章璐璐 张冠群 罗蔚锋
机构地区 苏州大学附属第二医院神经内科 徐州市中心医院神经内科
出处 《国际老年医学杂志》 2013年第5期218-222,共5页 International Journal of Geriatrics
基金 江苏省自然科学基金项目（BK2010229） 苏州市科技支撑计划项目（SS201112） 苏州大学莙政基金项目
关键词 帕金森病 多巴胺能神经元 尿酸 神经保护 Parkinson＇ s disease Dopaminergic neurons Uric acid Nerve effect
分类号 R971 [医药卫生—药品]
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参考文献5

二级参考文献41

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共引文献67

同被引文献37

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国际老年医学杂志
2013年 第5期

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