CRP在儿童急性呼吸道感染疾病中的应用

Application of CRP in Children with Acute Respiratory Tract Infection

目的探讨CRP在儿童急性呼吸道感染疾病中的应用。方法选取2010年3月至2012年3月我院收治的78例急性呼吸道感染患儿为研究对象,并取同一时期78例健康体检儿童为对照组。78例急性呼吸道患儿根据感染类型,可分为细菌感染组(28例)、支原体感染组(31例)和病毒感染组(19例),对78例患儿进行72h抗生素治疗。患儿及健康体检儿童入院时采集静脉血,且患儿抗生素治疗72h后静脉采血,检测其血清CRP水平。结果与对照组相比,病毒感染组CRP无明显差异(P>0.05),细菌感染组和支原体感染组CRP明显较高(P<0.05);经抗生素治疗后,78例患儿CRP明显下降。结论 CRP在儿童急性呼吸道感染疾病中可作为鉴别细菌感染、支原体感染及病毒感染的指标,同时可指导临床抗生素应用,因此,值得临床推广和应用。

Objective To explore the application of CRP in children with acute respiratory tract infection. Methods Select 78 patients with acute respiratory tract infection from March 2010 to March 2012 as the research object, and at the same period select 78 patients as control group. 78 patients can be divided into bacterial infection group （28 cases）, mycoplasma infection group （31 cases） and viral infection group （19 cases）, after 72 hours of antibiotics children and healthy children were collected venous blood,detect the level of serum CRP. Results Compared with the control group, the CRP in group virus infection had no significant difference （P〉0.05）, the CRP in bacterial infection group and mycoplasma infection in group was significantly higher （P〈0.05）; after antibiotic treatment, 78 cases of children with CRP was significantly decreased. Conclusion CRP in the disease can be used to identify bacterial infection, mycoplasma infection and virus infection in children with acute respiratory tract infection, also can be used to guide the clinical application of antibiotics, therefore, is worth the clinical promotion and application.