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Non-coding RNA annotation:Deciphering the second genetic code 被引量:3

Non-coding RNA annotation: Deciphering the second genetic code
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摘要 "Why do humans have so few 125 most compelling questions genes?" This is one of the that will face scientific in- quiry over the next quarter-century, according to the list collected by Science in 2005. As we know from the Human Genome Project, less than 2% of the human genome con- tains protein-coding genes, while the other 98% is com- posed of non-protein-coding DNA regions. However, what if there are hidden treasures besides DNA elements for rep- lication or transcription? Therefore, the investigation of "the dark genome" was placed in the top 10 "Insights of the decade" that Science released in 2010. Scientists have dis- covered that innumerable non-protein-coding RNA (ncRNA) genes, which were previously thought to be "junk DNA'" in the genome, are actually transcribed and may bestow im- portant biological functions. "Why do humans have so few genes?"This is one of the125 most compelling questions that will face scientific inquiry over the next quarter-century,according to the list collected by Science in 2005.As we know from the Human Genome Project,less than 2%of the human genome contains protein-coding genes,while the other 98%is composed of non-protein-coding DNA regions.However,
作者 QU LiangHu
出处 《Science China(Life Sciences)》 SCIE CAS 2013年第10期865-866,共2页 中国科学(生命科学英文版)
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