左氧氟沙星三联疗法与阿莫西林三联疗法治疗消化性溃疡的疗效比较

Effect comparsion of levofloxacin triple therapy with amoxicillin triple therapy in treatment of peptic ulcer

目的对左氧氟沙星三联疗法和阿莫西林三联疗法治疗消化性溃疡的效果进行对比分析。方法将收治的150例消化性溃疡患者随机分为观察组与对照组,观察组给予左氧氟沙星、奥美拉唑、呋喃唑酮三联疗法给药。对照组给予阿莫西林、奥美拉唑、呋喃唑酮三联疗法给药。结果观察组总有效率91.5%,对照组88.3%,两给相比有统计学意义(P<0.05);对照组不良反应发生率为12.8%,观察组为9.3%,两组比较无统计学意义(P>0.05)。结论左氧氟沙星三联疗法疗效显著,不良反应较小,是针对于阿莫西林耐药患者的最佳选择。

Objective The effect of levofloxacin triple therapy and amoxiciUin triple therapy in peptic ulcer were ana- lyzed. Methods Totally 150 patients with peptic ulcer admitted patients were randomly divided into observation group and the control group, the observation group were given levofloxacin triple therapy administered levofloxacin, omeprazole, furazolidone. The control group was given amoxicillin triple therapy administered amoxicillin, omeprazole, furazolidone. Results Efficacy for the observation group total efficiency of 91.5% in the control group, the total efficiency, compared to 88. 3 % , there is a statistically significant （P 〈 0. 05 ） ;On adverse events, the occurrence of adverse reactions of the observation group experimental group of adverse occurrence rate was 9. 3%, 12. 8%, the diffenence not statistically sig- nificant, the price, the observation group medication than the experimental group more affordable. And intestinal fungus easy to become resistant to amoxicillin and levofloxacin sensitive. Conclusion Compared with amoxicillin triple thera- py, levofloxacin triple therapy with better efficacy and less adverse reactions, the price is more affordable, is the best choice for amoxicillin -resistant patients.