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高危型人乳头瘤病毒E6、E7mRNA检测筛检宫颈癌的价值 被引量:4

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摘要 宫颈癌是一种严重危害女性健康的恶性肿瘤,其发病率位居女性恶性肿瘤的第2位。自德国医学家HaraldzurHausen20世纪70年代提出人乳头瘤病毒(humanpapillomavirus,HPV)可能导致宫颈癌,至今已有大量流行病学和分子生物学研究证实旧。川:高危型HPV持续感染促使宫颈细胞发生恶性转化,并维持细胞恶性表型的持续表达,是宫颈上皮内瘤变(cervicalintraepithelialneoplasia,CIN)及宫颈癌发生、发展的首要病因。
出处 《中国实用妇科与产科杂志》 CAS CSCD 北大核心 2013年第10期837-840,共4页 Chinese Journal of Practical Gynecology and Obstetrics
关键词 人乳头瘤病毒 E6 E7 宫颈肿瘤 human papillomavirus E6.E7 uterine cervical neoplasm
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  • 1Li J, Li LK, Ma JF, et al. Knowledge and attitudes about human papillomavirus (HPV) and HPV vaccines among women living in metropolitan and rural regions of China [ J ]. Vaccine, 2009, 27(8) :1210-1215.
  • 2Woodman CB, Collins SI, Young IS. The natural history of cervical HPV infection: unresolved issues [ J ]. Nat Rev Cancer, 2007, 7(1) :11-22.
  • 3Munoz N, Bosch FX, De Sanjos S, et al. Epidemiologic classification of human papillomavirus types associated with cervical cancer [J]. N Engl J Med, 2003, 348(6) :518-527.
  • 4Narisawa-Saito M, Kiyono T. Basic mechanisms of high-risk human papillomavirus induced carcinogenesis: roles of E6 and E7 proteins [ J ]. Cancer Sci, 2007, 98 (10) : 1505-1511.
  • 5Boulet GA, Horvath CA, Berghmans S, et al. Human papillomavirus in cervical cancer screening:important role as biomarker [J]. Cancer Epidemiol Biomarkers Prev, 2008,17 (4) :810- 817.
  • 6赖年钰,喻垚,牟江涛,吴立翔.人乳头瘤病毒检测研究进展[J].重庆医学,2011,40(30):3105-3107. 被引量:7
  • 7梁东霞(综述),张彦娜(审校).宫颈癌与hpv关系的研究进展[J].实用癌症杂志,2010,25(2):202-205. 被引量:56
  • 8Franco EL, Ferenczy A. Cervical cancer screening following the implementation of prophylactic human papillomavirus vaccination [J]. Future Oncol, 2007, 3(3) :319-327.
  • 9Brink AA, Snijders PJ, Meijer C J, et al. HPV testing in cervical screening [ J]. Best Pract Res Clin Obstet Gynaecol, 2006, 20(2) :253-266.
  • 10Khan MJ, Castle PE, Lorincz AT, et al. The elevated 10-year risk of cervical precancer and cancer in women with human papillomavirus (HPV) type 16 or 18 and the pessible utility of type-specific HPV testing in clinical practice [J]. J Natl Cancer Inst, 2005, 97(14) :1072-1079.

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