慢性阻塞性肺疾病急性加重期至缓解期证素变化研究

Study on Syndrome Elements Transition from Acute Exacerbation Stage to Stable Stage of Chronic Obstructive Pulmonary Disease

目的:探讨慢性阻塞性肺疾病急性加重期至缓解期病机转归。方法:收集120例慢性阻塞性肺疾病患者四诊情况,软件录入分析得出证素名称,采用自身前后对照分析。结果:70分以上的证素积分从高往低的分布频率前5位为:病位:急性期依次为肾>肺>心>脾>表;缓解期依次为肺>肾>心>脾>表。病性:急性期依次为气虚=痰>阳虚>血虚>阴虚;缓解期依次为气虚>阳虚>痰>阴虚>血虚。病性等级急性加重期气虚重度占94%,痰重度占73.6%,血虚中度占28.3%。缓解期气虚重度41.5%,痰中度30.2%,血虚轻度占30.2%。结论:COPD病位在肾、肺、心为主,急性加重期到缓解期病位变化由肾转到肺为主,病性均以气虚、痰、阳虚、血虚、阴虚为主,但病性程度变化大。其中以痰、血虚变化最突出。

Objective ： To explore the syndrome elements transition from acute exacerbation stage to stable stage of chronic obstructive pulmonary disease （ COPD ）. Methods ： The data of 120 cases of COPD patients was inputted into the software systems by using the method of TCM syndrome elements to draw the name of the syndrome elements which named syndrome elements by self controlled method. Results ： It showed that top 5 of the syndrome elements frequency more than 70 points were as follows ： location： acute stage ： kidney〉lung〉heat〉spleen〉exterior ; stable stage ： lung〉kidney〉heart〉spleen〉exterior ; nature ： acute stage： Qi deficiency= phlegm〉Yang deficiency〉blood deficiency〉Yin deficiency; stable stage： Qi deficiency〉Yang deficiency〉phlegm〉Yin deficiency〉blood deficiency; nature grade： acute stage： severe Qi deficiency was 94%, the severe phlegm was 73.6%, moderate blood deficiency was 28.3%; stable stage： severe Qi deficiency was 41.5%, moderate phlegm was 30.2%, mild blood deficiency was 30.2%. Conclusion： COPD position was mainly kidney, lung and heart. Changes were mainly from kidney to lung. Disease natures were mainly Qi deficiency, phlegm, Yang deficiency, blood deficiency, Yin deficiency, phlegm and blood deficiency are more obvious.