摘要
目的:观察血流方时肾虚血瘀型冻融胚胎移植周期患者子宫内膜的容受性的影响。方法:收集复苏移植周期中子宫内膜发育不良的肾虚血瘀型不孕症患者80例,随机分为2组,观察组40例,于月经干净开始服血流方,每日1剂,用至移植日;月经第3天口服戊酸雌二醇片,每日2次,每次2 mg;对照组40例,月经第3天开始口服戊酸雌二醇片,每日2次,每次2 mg。移植后均加用黄体酮,每日1次,每次肌肉注射60 mg;肌肉注射HCG,隔日1次,每次2000 U,用3 d。于月经第2天、移植前1天监测子宫内膜类型及厚度和子宫内膜下的血流参数,同时随访两组的妊娠结局。结果:治疗后两组患者子宫内膜厚度及类型比较差异显著(P<0.05)。治疗后两组患者子宫内膜下血流参数比较差异有统计学意义(P<0.05);观察组妊娠率高于对照组,差异显著(P<0.01)。结论:血流方能改善复苏移植周期中子宫内膜的生长,改善子宫内膜类型及子宫内膜下血流情况,有利于胚胎着床,提高临床妊娠率。
Objective : To observe the effects of Xueliu^ang on endometrial receptivity of kidney deficiency and blood stasis type patients with infertility in the frozen-thawed embryo transfer cycle. Method : Choosing a sample of 80 kidney deficiency and blood stasis type patients with infertility whose endometrium was undergrown, in the next frozen-thawed embryo transfer cycle,they were randomly divided into two groups : 40 cases of observation group, taking a course of treatment of Xueliufang from the menstrual clean day, one dose daily, until the frozen-thawed embryo transfer day ; 40 cases of control group, taking estradiol valerate tablets from the third day of menstrual cycle,2 mg once, twice a day. After transplantation, they need to inject progesterone 60 mg one day and HCG 2000 U every other day, using 3 days. Monitor the type and thickness of endometrium and blood flow parameters under endometrial on the second day of menstrual cycle and before frozen-thawed embryo transfer day, while follow-up pregnancy outcomes of the two groups. Result: After the administration of drugs, endometrial thickness and type of the two groups have been improved, and the comparative differences between treatment and control groups were statistically significant (P〈0.05); blood flow parameters under endometrial of treatment was lower than that of the control group ( P〈0.05 ); the pregnancy rate of the observation group was significantly higher than that of the control group ( P〈0.01 ) .Conclusion : Xueliufang can promote the growth of the endometrium in frozen-thawed embryo transfer cycle, improve the type of endometrium and blood flow parameters under endometrium, facilitate embryo implantation, and then increase clinical pregnancy rates.
出处
《辽宁中医药大学学报》
CAS
2013年第10期183-184,共2页
Journal of Liaoning University of Traditional Chinese Medicine
关键词
血流方
冻融胚胎移植周期
子宫内膜容受性
Xueliufang
frozen-thawed embryo transfer cycle
endometrial receptivity