期刊文献+

血流方对肾虚血瘀型冻融胚胎移植患者子宫内容受性影响 被引量:3

Observation on influence of Xueliufang on Endometrial Receptivity of Kidney Deficiency and Blood Stasis Type Patients with Infertility in Frozen-thawed Embryo Transfer Cycle
下载PDF
导出
摘要 目的:观察血流方时肾虚血瘀型冻融胚胎移植周期患者子宫内膜的容受性的影响。方法:收集复苏移植周期中子宫内膜发育不良的肾虚血瘀型不孕症患者80例,随机分为2组,观察组40例,于月经干净开始服血流方,每日1剂,用至移植日;月经第3天口服戊酸雌二醇片,每日2次,每次2 mg;对照组40例,月经第3天开始口服戊酸雌二醇片,每日2次,每次2 mg。移植后均加用黄体酮,每日1次,每次肌肉注射60 mg;肌肉注射HCG,隔日1次,每次2000 U,用3 d。于月经第2天、移植前1天监测子宫内膜类型及厚度和子宫内膜下的血流参数,同时随访两组的妊娠结局。结果:治疗后两组患者子宫内膜厚度及类型比较差异显著(P<0.05)。治疗后两组患者子宫内膜下血流参数比较差异有统计学意义(P<0.05);观察组妊娠率高于对照组,差异显著(P<0.01)。结论:血流方能改善复苏移植周期中子宫内膜的生长,改善子宫内膜类型及子宫内膜下血流情况,有利于胚胎着床,提高临床妊娠率。 Objective : To observe the effects of Xueliu^ang on endometrial receptivity of kidney deficiency and blood stasis type patients with infertility in the frozen-thawed embryo transfer cycle. Method : Choosing a sample of 80 kidney deficiency and blood stasis type patients with infertility whose endometrium was undergrown, in the next frozen-thawed embryo transfer cycle,they were randomly divided into two groups : 40 cases of observation group, taking a course of treatment of Xueliufang from the menstrual clean day, one dose daily, until the frozen-thawed embryo transfer day ; 40 cases of control group, taking estradiol valerate tablets from the third day of menstrual cycle,2 mg once, twice a day. After transplantation, they need to inject progesterone 60 mg one day and HCG 2000 U every other day, using 3 days. Monitor the type and thickness of endometrium and blood flow parameters under endometrial on the second day of menstrual cycle and before frozen-thawed embryo transfer day, while follow-up pregnancy outcomes of the two groups. Result: After the administration of drugs, endometrial thickness and type of the two groups have been improved, and the comparative differences between treatment and control groups were statistically significant (P〈0.05); blood flow parameters under endometrial of treatment was lower than that of the control group ( P〈0.05 ); the pregnancy rate of the observation group was significantly higher than that of the control group ( P〈0.01 ) .Conclusion : Xueliufang can promote the growth of the endometrium in frozen-thawed embryo transfer cycle, improve the type of endometrium and blood flow parameters under endometrium, facilitate embryo implantation, and then increase clinical pregnancy rates.
出处 《辽宁中医药大学学报》 CAS 2013年第10期183-184,共2页 Journal of Liaoning University of Traditional Chinese Medicine
关键词 血流方 冻融胚胎移植周期 子宫内膜容受性 Xueliufang frozen-thawed embryo transfer cycle endometrial receptivity
  • 引文网络
  • 相关文献

参考文献3

  • 1欧阳惠卿.中医妇科学[M].北京:人民卫生出版社,2004:123.
  • 2Achache H, Revel A.Endometrial receptivity markers, the journey to successful embryo implantation[ J ] .Hum Reprod Update, 2006,12 ( 6): 731-746.
  • 3Merc 6 LT, BarcoMJ, Bau S, et al.Are endometrial parametersby three-dimensional ultrasound and power Doppler angiographyrelated to in vitro fertilization/embryo transfer outcomeS- J ] .Fertil Streril, 2008,89 ( 1 ) : 111-117.

共引文献12

同被引文献38

  • 1A1-Ghamdi A, Coskun S, A1-Hassan S, et al. The correlation between endometrial thickness and outcome of invitro fertilization and embryo transfer (IVF-ET) outcome. Reprod Biol Endocinol, 2008, 6(37): 1-5.
  • 2Higgins JPT, Green S (editors). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 [updated March 2011].The Cochrane Collaboration, 2011. Available at: www. cochranehandbook.org.
  • 3马翠霞.定坤丹对子宫内膜发育不良不孕患者的临床疗效观察.中医中药,2013,(1):260.261.
  • 4Wang L, Qiao J, Li R, et al. Role of Endometrial blood flow assessment with color Doppler energy in predicting pregnancy outcome of IVF-ET cycles. Reprod Biol Endocrinol, 2010, 8(1): 122.
  • 5Lilic V, Tubic-Pavlvic A, Radovic-Janosevic D, et al. Assessment of endometrial receptivity by color Doppler and ultrasound imaging. Med Pregl, 2007, 60(5-6): 237-240.
  • 6Amir W, Micha B, Ariel H, et al. Predicting factors for endometrial thickness during treatment with assisted reproductive technology. Fertil Sterih 2007, 87: 799-804.
  • 7高喜红.补肾养血中药在体外受精-胚胎移植中的疗效观察[J].中国中医药科技,2014,4(z1):47-48.
  • 8罗江霞,覃爱平,张海英.子宫内膜厚度与容受性的研究[J].实用妇产科杂志,2010,26(8):608-610. 被引量:13
  • 9刘昱磊,王俊玲,滕辉.活血补肾方治疗子宫内膜生长不良性不孕症30例[J].陕西中医学院学报,2011,34(1):60-61. 被引量:14
  • 10刘艳,席丽军.紫河车胶囊用于治疗子宫内膜过薄不孕症的探讨[J].中医药信息,2011,28(4):118-119. 被引量:12

引证文献3

二级引证文献17

;
使用帮助 返回顶部