失血性休克后液体复苏的研究进展

Advances in fluid resuscitation after hemorrhagic shock

背景失血性休克是外伤死亡的主要原因。在重危病例的急救和围手术期的处理中，液体复苏起着关键性的治疗作用。目的就重度失血性休克后液体治疗方案的研究进展作一综述。内容除了传统的晶体液，近年来开发了诸多新品种的液体用于复苏，如丙酮酸钠溶液等。复苏方式的研究也在静脉复苏的基础上拓展到了腹腔复苏。趋向丙酮酸钠溶液以及腹腔复苏是近年来研究提出的新的复苏液体和复苏方案，通过已有的研究已经证实其积极的治疗作用。其应用于失血性休克的方法、时间、疗效等仍需更进一步研究。

Background Hemorrhagic shock is the primary cause of death in trauma. In emergency treatment of severe patients and the perioperative treatment, fluid resuscitation plays a crucial role. Objective This review summarizes the advances in fluid therapy after refractory hemorrhagic shock. Content In recent years, in addition to the traditional crystalloid solution, many new varieties of solution are used to resuscitate, including sodium pyruvate. And the methods of fluid resuscitation are expanded to intraperitoneal resuscitation from intravenous fluid resuscitation. Trend Sodium pyruvate is a new kind of fluid used for resuscitation in recent studies, and intraperitoneal resuscitation is a new method of resuscitation. New researches have confirmed that they have positive effects in fluid resuscitation. However, the processes, time and curative effect of them still need further research.