急性肝衰竭患儿肠内营养干预研究

Enteral Nutritional intervention in pediatric patients with acute liver failure

目的探讨营养干预对急性肝衰竭患儿临床转归的影响。方法针对不同年龄段患儿,采用个体化营养干预、营养状况动态监测等方法,并根据患儿不同病程阶段进行营养素摄入量调整。结果营养干预后,患儿肝功能指标得到不同程度改善,其中反映肝脏合成功能的白蛋白及纤维蛋白等营养相关指标改善显著。结论及时有效的营养干预对恢复患儿正氮平衡、提高机体耐受能力、改善临床结局具有研究价值,值得深入探讨。

Objective To analyze the impact of nutritional interventions as part of treatment on clinical outcomes in pediatric patients with acute liver failure. Methods Based on pediatric patients＇ age groups, we used personalized nutritional interventions, conducted nutritional dynamic monitoring, and adjusted the amount of nutrient intake according to their varying disease stages. Results After nutritional interventions, liver functions of patients were improved ; Nutritional status indicators reflecting liver synthesis as serum albumin and fibrin were significantly improved. Conclusions Timely, effective nutritional intervention could improve tile recovery of positive nitrogen balance, tolerance, and clinical outcomes in pediatric patients with acute liver failure, whieh is worthy of further discussion.