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地佐辛复合依托咪酯用于宫腔镜检查中的麻醉效果及安全性 被引量:4

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摘要 目的观察地佐辛复合依托咪酯用于宫腔镜检查的麻醉效果及安全性。方法选择行静脉麻醉下宫腔镜检查的患者60例,随机分成两组,依托咪酯组(E组)和地佐辛复合依托咪酯组(DE组),每组各30例,依托咪酯组(E组)直接注入依托咪酯0.3 mg/kg,速度为30~60 s,地佐辛复合依托咪酯组(DE组)先静脉滴注地佐辛0.1 mg/kg,待5分钟后静注依托咪酯0.3 mg/kg,速度为30~60 s,记录麻醉前T1、麻醉后5分钟T2、扩宫颈时T3、入镜后5分钟T4、10分钟后T5、术毕时T6、各时间点的MAP、HR、SpO2,观察并记录手术时间(从扩宫至术毕)、清醒时间(术毕呼之睁眼至定向力恢复)、术中肌阵挛发生率、清醒后10分钟下腹疼痛的发生率及依托咪酯的总用量。结果两组间麻醉效果的比较,评定优的例数DE组明显多于E组,差异有统计学意义(P〈0.01)。肌阵挛率发生率DE组明显少于E组,差异有统计学意义(P〈0.01)。术后10分钟下腹疼痛的VAS评分DE组与E组组间比较,差异有统计学意义(P〈0.01)。两组依托咪脂的总用量是DE组明显少于E组,组间比较差异均有统计学意义(P〈0.01)。结论地佐辛复合依托咪酯用于宫腔镜检查优于单纯使用依托咪酯,是一种可靠安全的麻醉方法,值得推广。
出处 《齐齐哈尔医学院学报》 2013年第17期2537-2538,共2页 Journal of Qiqihar Medical University
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