重症监护医学科感染铜绿假单胞菌特点及其耐药性

STUDY ON CHARACTERISTICS OF INFECTION AND RESISTANCE OF Pseudomonas Aeruginosa IN ICU

目的了解医院重症医学科铜绿假单胞菌的感染分布特点及耐药性变化,指导抗菌药物合理使用。方法通过资料调查和细菌学检测,对某医院重症医学科住院患者医院感染与送检标本检测结果进行了调查。结果该医院重症医学科2010-2011年连续2年从医院感染患者送检标本中共检出铜绿假单胞菌267株,呼吸道标本检出比例最高,占74.2%。临床分离的铜绿假单胞菌对替卡西林/棒酸耐药率最高,达75.66%;其次是头孢曲松、氨曲南、哌拉西林,耐药率均在50%以上。结论重症医学科内铜绿假单胞菌的感染以呼吸道为主,耐药现象日趋严重,应根据药敏结果选用抗菌药物。

Objective To investigate distribution characteristics of infection and resistance of Pseudomonas aeruginosa in ICU, and instruct the antibacterial drug to use rationally. Methods Data investigation and detection of bacteriology were used to investigate the nosocomial infection in hospitalized patients in the ICU and the samples. Results Between 2010 and 2011, 267 strains Pseudomonas aeruginosa were detected out from the nosocomial infection samples. Respiratory tract specimens detection has the highest proportion, which accounting for 74. 2%. The resistant rate of clinical isolated Pseudomonas aeruginosa for ticarcillin/rod acid is highest, which accounting for 75.66%. Followed by ceftriaxone, ammonia QuNa, piperacillin were above 50%. Conclusions Pseudomonas aeruginosa infection was mainly from respiratory tract in ICU; Pseudomonas aeruginosa resistance phenomenon is increasingly serious, we should choose drug according to the resuits of drug sensitive.