乳酸菌抑制致病菌黏附作用机制研究进展

The development of the Lactobacillus adhensive effects mechanism in inhibiting the pathogen microorganism

乳酸菌是人类和动物小肠道中的优势菌群,对抑制病原菌的入侵与感染和维持消化道内微生物区系平衡等都具有重要意义。乳酸菌依靠其表面的蛋白、多糖等黏附宿主肠上皮细胞,使其定植进而发挥抑制致病菌黏附和抑制致病菌生长等重要生理作用。本文就乳酸菌表面与黏附相关的因子及其抑制致病菌黏附和抑制致病菌生长的作用机制进行综述。

Lactic acid bacteria is the predominant bacterium in the small intestine of human being and animals, which inhibit the pathogen＇s invasion and infection and take a great significance to maintain the balance of digestive tract. The precondition of the anti-pathogen is by mean of the mechanism that lactobacillus can bind on the surface of the intestinal tract＇s epithelium by their surface protein and polysaccharide,then form the predominant bacterium,which take a antagonistic action. Various factors about adhesion and the mechanism of the lactobacillus aaainst the pathoaenic bacteria were reviewed in this ~aoer.