败血症老年患者血清降钙素原水平及临床意义

Serum procalcitonin levels and its clinical significance in elderly patients with sepsis

目的血清降钙素原（PCT）在老年败血症中早期诊断价值。方法采用双抗夹心免疫法对91例老年重症患者进行PCT测定，并根据临床和生理指标，将91例患者分为败血症组48例：其中包括血培养确诊的败血症25例（A组）．临床败血症23例（B组）；非败血症组43例：其中包括存在局部感染但不存在败血症19例（C组），无感染24例（D组）。结果败血症组PCT明显升高，非败血症组PCT仅轻度升高或不升高，二者比较差异有统计学意义（P〈0．05）。结论PCT可作为老年败血症早期诊断重要的指标，为临床合理应用抗生素提供较好的依据。

Objective To investigate the early diagnosis value of PCT in elderly patients with sepsis . Methods Ninety-one elderly patients with severe illness were given PCT test by the double anti sandwich immune method, and according to the clinical and physiological indicators, 91 cases were di- vided into sepsis group（48 cases） ： including blood culture diagnosed sepsis in 25 cases （ group A） , clinical sepsis in 23 cases （group B） ; Non-sepsis groups（43 cases） , including the existing local in- fection, but there were no septicemia in 19 cases （ C group） , no infection in 24 cases （ group D）. Results Sepsis group of PCT increased significantly, the non-sepsis group of PCT mildly rise or not rise, but the difference was statistically significant between the two groups. Conclusions PCT can serve as important indicators of early diagnosis of sepsis in the elderly patients, and could provid ra-tional application of antibiotics.