原发性输卵管癌27例临床病例分析

Analysis of 27 cases primary carcinoma of fallopian tube

目的本文探讨原发性输卵管癌的临床表现、肿瘤标志物、病理及治疗。方法回顾性分析我院2010年7月～2012年7月收治的27例原发性输卵管癌患者的临床资料。结果患者平均年龄56岁，其中21例为绝经后妇女。27例患者中4例有阴道排液，10例有阴道流血，3例有腹痛，5例腹胀，1例尿频，13例有腹水，2例感纳差恶心，1例感腰酸，2例有消瘦，4例无症状仅查体发现盆腔肿物。病理：浆液性腺癌22例，子宫内膜样腺癌2例，混合性腺癌2例，透明细胞癌1例。FIGO分期：I期5例，Ⅱ期2例，Ⅲ期18例，Ⅳ期2例。结论原发性输卵管癌典型症状少见，易误诊，恶性度高，晚期病例多。应努力提高原发性输卵管癌的诊断率。治疗方法为手术及化疗。

Objective This article discussed the clinical presentation,tumor markers,clinicopathologic features and treatment of Primary fallopian tube carcinoma （PFTC）. Methods Twenty-seven patients with PFFC treated at our hospital were retrospectively analyzed. Results The mean age of these patients was 56 years. Twenty-one were menopausal women. The clinical manifestations of 27 PFFC were as followed： vaginal discharge （4 cases）, vaginal bleeding （10 cases）, abdominal pain （3 cases）, abdominal distension （5 cases）, frequency of micturition（lcase）,ascites（13eases）, anorexia and nausea （2 cases）, backache （1 case）, weight loss （2 cases）, with no symptoms （4 cases）. Clinicopathologic features showed serous adenoeareinoma in 22, endometrioid adenoearcinoma in 2,mixed adenocarcinoma in 2 and clear cell carcinoma in 1 patients. FIGO stages：5 patients in stage I ,2 in stage H ,18 in stage HI, and 2 in stage IV. Conclusion The typical clinical symptoms of PFTC is rare, early diagnosis difficult.Preoperative diagnosis of the disease is extremely rare.Patients are often diagnosed at advanced stages. It is important to improve the diagnosis rate of PFFC. Surgery and chemotherapy are main therapy for this disease.