丽水地区健康人血清25-羟基维生素D水平季节性分析

Seasonal variation of 25- hydroxy vitamin D levels in healthy human sera from Lishui

目的探讨丽水地区健康人群血清25-羟基维生素D(25-OHD)水平季节性差异。方法采用电化学发光免疫分析法对2316例健康体检人员血清25-羟基维生素D进行分析,并以性别、季节进行分组比较。结果男性血清25-OHD水平充足、不足、缺乏依次为32.33%、32.12%和35.54%,女性25-OHD水平充足、不足、缺乏依次为27.46%、26.67%和45.85%,春夏秋冬四季人群血清25-OHD水平分别为(20.4±10.7)、(34.6±14.2)、(24.4±11.0)、(19.4±10.0)ng/ml。结论 25-OHD水平缺乏女性明显高于男性,另外春冬季节25-OHD水平明显低于夏秋季节,因此春冬季节要特别注意25-羟基维生素D的补充。

Objective TO investigate the seasonal variation of 25 - hydroxy vitamin D （25 - OHD） level in healthy human se- ra from Lishui. Methods 25 - OHD in 2316 healthy human sera were detected by electrochemiluminescence immunoassay and compared in groups of sex and seasons. Results The percentages for male with sufficient, insufficient and lack of 25 - OHD levels were 32.33%, 32. 12% and 35.54%, respectively. While the percentages for women were 27.46% , 26.67% and 45.85 % , respectively. The concentration of 25 - OHD in spring, summer, autumn and winter were （20.4 ± 10.7 ） , （ 34.6 ±14.2）, （24.4 ±11.0） and （19.4 ±10.0） ng/ml,respectively. Conclusion The insufficient percentage of 25 -OHD in fe- male sera were higher than that in male. In spring and winter, the level of 25 - OHD in sera was significantly lower than that in summer and autumn.