microRNAs与原发性肝细胞肝癌相关性的研究进展
Advances in Research of Relationship between MicroRNAs and Primary Hepatocellular Carcinoma
摘要
microRNAs(miRNAs)可通过调控其靶标基因参与的信号通路影响肿瘤的发生和发展,发挥类似于癌基因或抑癌基因的功能。本文就目前miRNAs在原发性肝细胞肝癌(hepatocellular carcinoma,
出处
《中国临床医学》
2013年第4期605-607,共3页
Chinese Journal of Clinical Medicine
参考文献18
-
1Tsai WC, Hsu SD, Hsu CS,et al. MicroRNA-122 plays a criti- cal role in liver homeostasis and hepatocarcinogenesis[J]. J Clin Invest, 2012,122 (8) : 2884-2897.
-
2Fornari F,Gramantieri L,Giovannini C,et al. MiR-122/cyclin G1 interaction modulates p53 activity and affects doxorubicin sensitivity of human hepatocarcinoma cells[J]. Cancer Res, 2009,69(14) : 5761-5767.
-
3Callegari E,Elamin BK,Giannone F,et al. Liver tumorigenici- ty promoted by microRNA-221 in a mouse transgenic model [J]. Hepatology,2012,56(3) : 1025-1033.
-
4Gramantieri L, Fornari F, Ferracin M, et al. MicroRNA-221 targets Bmf in hepatocellular carcinoma and correlates with tumor multifocality[J]. Clin Cancer Res, 2009,15(16):5073 -5081.
-
5Galardi S,Mercatelli N,Giorda E,et al. miR-221 and miR-222expression affects the proliferation potential of human pros- tate carcinoma cell lines by targeting p27Kipl [J]. J Biol Chem,2007,282(32) :23716-23724.
-
6Fornari F,Gramantieri L,Ferracin M,et al. MiR-221 controls CDKN1C/p57 and CDKN1B/p27 expression in human hepa- tocellular carcinoma[J]. Oncogene, 2008,27 (43) : 5651-5661.
-
7Medina R, Zaidi SK, Liu CG, et al. MicroRNAs 221 and 222 bypass quiescence and compromise cell survival[J]. Cancer Res, 2008,68 (8) ; 2773-2780.
-
8Garofalo M, Di Leva G, Romano G, et al. miR 221 &222 regu- late TRAIL resistance and enhance tumorigenicity through PTEN and TIMP3 downregulation[J]. Cancer Cell, 2009,16 (6) :498-509.
-
9Pineau P, Volinia S, McJunkin K, et al. miR-221 overexpres- sion contributes to liver tumorigenesisFJ~. Proc Natl Acad Sci U S A,2010,107(1):264-269.
-
10Meng F, Henson R, Wehbe-Janek H, et al. MicroRNA-21 reg ulates expression of the PTEN tumor suppressor gene in hu- man hepatocellular cancer[J]. Gastroenterology, 2007, 133 (2) :647-658.
-
1商进春,徐凤珍.肺癌相关性肾病综合征2例报告[J].山东医药,2009,49(35):18-18. 被引量:1
-
2庄天微,乔虹.PIK3CA、CCL5、Survivin基因与甲状腺癌相关性的新发现[J].标记免疫分析与临床,2014,21(1):12-14. 被引量:1
-
3陈姣艳,廖爱军.cyclin D1、p16与胃癌相关性的研究进展[J].现代医药卫生,2010,26(5):725-726.
-
4李亚楠,王洪武.抑癌基因PTEN与非小细胞肺癌相关性研究进展[J].中国肺癌杂志,2014,17(3):260-264. 被引量:11
-
5郭琴,董跃强.生存素 血管内皮生长因子在乳腺导管癌中的表达及临床分析[J].中国药物与临床,2007,7(2):121-122.
-
6周兴舰,李红浪.微小RNA功能失调与胃癌相关性研究进展[J].实用医学杂志,2011,27(17):3253-3255. 被引量:4
-
7陈国荣,刘霞.癌相关性视网膜病变2例[J].眼科新进展,1998,18(3):184-184.
-
8高会会,张志明.DcR3与乳腺癌相关性研究进展[J].实用医学杂志,2011,27(6):1101-1102.
-
9梁海慧,张月飞.抑癌基因p16与鼻咽癌相关性的研究进展[J].广东医学,2007,28(7):1194-1196. 被引量:3
-
10徐东亮,夏术阶.保留肾单位手术的发展和值得注意的问题[J].上海医学,2014,37(3):188-191.