复治肺结核的耐药状况及疗效分析

Analyzing of Treatment Effect in Recurrence of Pulmonary Tuberculosis for drug-Resistant

目的:对复治肺结核患者治疗情况进行总体分析。方法:对2011—2012年长沙市中心医院登记治疗的复治肺结核患者进行分析。对126例复发肺结核患者使用罗氏培养基比例法进行痰结核菌培养,了解是否进行药物敏感试验,对114例患者使用WHO积极推荐的规范化复治短期化疗方法进行全过程一体化监督治疗管理。结果:126例复发肺结核病例总耐药率为57.14%,同时对HR耐药的耐药率为34.13%;114例复发肺结核病例治愈率为51.75%。结论:复发肺结核患者耐药情况相对较高,治愈率相对较低。复治涂阳的原因主要有用药不太合理、患者治疗不连续、用药无规律。在今后的复发肺结核病例的诊疗过程中应加大力量提高治愈率。

Objective： To understand the situation in treatment of the recurrence of pulmonary tuberculosis. Methods ： Analyzed the patients of Changsha central hospital with the recurrence of pulmonary tuberculosis in 2011 -2012. Sputum tuberculosis bacteria and drug sensitive tests were carried in 126 patients with the method of LUOSHI. And 114 cases were adopted in standard treat method of WHO. All the process were recorded. Results：Drug resistance ratio of 126 cases was 57.14%. Resistance ratio for HR was 34.13%. Recovery rate of 114 cases was 51.75 %. Conclusions：Drug - resistant rate of tuberculosis in Changsha central hospital is higher. The treatment effect is not good （with low recover rate ）, and the main reasons for the recurrence of pulmonary tuberculosis are the improper medication and interrupted and irregular medication. We should try our best to improve the treatment rate and reduce drug - resistant opportunities and avoid recurrence of tuberculosis.