树突细胞在旋毛虫感染免疫中作用的研究进展

Research progress on the immunological effects of intestinal mucosal dendritic cells in Trichinella spi-ralis infection

旋毛虫病是一种常见的人兽共患寄生虫病，也是一种重要的食源性寄生虫病，严重危害着人体的健康。树突状细胞是固有性免疫细胞的一种，也是宿主肠道黏膜免疫系统最重要的一种抗原呈递细胞，与宿主肠道免疫系统关系密切。近年来有关树突状细胞在寄生虫感染与宿主免疫应答中的作用，尤其在旋毛虫感染与免疫的作用，备受人们的关注。该文就目前国内有关旋毛虫感染后．宿主树突状细胞参与肠黏膜的一系列免疫应答反应和发挥作用的研究进展做一综述。

Trichinosis is one of the most common zoonotic parasitic diseases, a kind of important food- borne parasitic disease with serious harm to human health. Dendritic cells are a kind of innate immune cells. As one of the most important antigen-presenting cells in the intestinal mucosal immune system of the host, it is closely related to the intestinal immune system. In recent years, its effect on parasite infection and host im- mune responses, especially in the Trichinella spiralis infection and immunity has attracted people＇s attention. In this review, the research progress at home and abroad on the host intestinal mucosal dendritic cells in- volved in a series of immunological reactions and roles in Trichinella infection was reviewed.