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乳腺癌干细胞分选及其异质性

Separation of breast cancer stem cell and its heterogeneity
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摘要 乳腺癌干细胞的成功分选是进行乳腺癌干细胞研究的基础，目前人们可以通过多种方法使乳腺癌干细胞得到一定程度的富集。然而，在越来越多乳腺癌干细胞表面标志物被发现的同时，其异质性也成为人们关注的热点。如何最大程度地富集乳腺癌干细胞及解释其异质性，将为乳腺癌的干细胞治疗提供新思路。 The successful separation of breast cancer stem cells （BCSCs） is the foundation of BCSC research. At present, people could gather BCSCs to some extent in a number of ways. However, as more and more biomarkers are found in BCSCs separation, the heterogeneity becomes a hot spot. How to gather BCSCs as much as possible and how to explain the heterogeneity could provide new insights in the treatment of breast cancer.
作者 孔冕 林雨 王军业 李宝江
机构地区 中山大学华南肿瘤学国家重点实验室 高血压研究所 山东省泰安市中心医院乳腺外科
出处 《国际肿瘤学杂志》 CAS 2013年第9期674-677,共4页 Journal of International Oncology
基金 广东省科技计划（20108031600066）
关键词 乳腺肿瘤 干细胞 生物学标记 遗传异质性 Breast neoplasms Stem cells Biological markers Genetic heterogeneity
分类号 R737.9 [医药卫生—肿瘤]
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参考文献28

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二级参考文献9

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国际肿瘤学杂志
2013年 第9期

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