期刊文献+

重症肺炎抗生素降阶梯疗法的疗效观察 被引量:12

下载PDF
导出
摘要 目的:评价重症肺炎采用抗生素降阶梯疗法与传统疗法的疗效对比。方法:将82例重症肺炎患者随机分为治疗组与对照组,每组41例,观察组采用抗生素降阶梯疗法,以亚胺培南/西司他丁为起始抗生素,对照组采用常规疗法,使用头孢哌酮/舒巴坦和阿米卡星,比较两组疗效和临床指标。结果:观察组总有效率为92.86%,显著高于对照组的78.05%(P<0.05),观察组APACHEⅡ评分下降率、机械通气时间、ICU住院时间、总住院时间、死亡率以及细菌清除率均优于对照组,差异有统计学意义(P<0.05)。结论:抗生素降阶梯疗法对重症肺炎疗效良好,可以显著降低死亡率和住院时间,值得推广应用。
作者 吕红丽
机构地区 重庆嘉陵医院
出处 《吉林医学》 CAS 2013年第27期5551-5552,共2页 Jilin Medical Journal
  • 引文网络
  • 相关文献

参考文献6

二级参考文献35

  • 1[4]Ibrahim EH,Sherman G,Ward S,et al.The influeuee of inadequate antimicrobial treatment of blood stream infections on patient outcomes in the ICU setting[J].Chest,2000,118(1):146-155
  • 2[5]Hartwog W,Wemer J,Muller CA.Surgical manage ment of severe pancreatitis including sterile necrosis[J].J Hepatobiliary Pancreat Surg,2002,9(4):429-435
  • 3KOLLEF MH,WARD S.The influence of mini BAL cultures on patient outcomes:implications for the antibiotic management of ventilator associated pneumonia[J].Chest,1998,113(2):412-420.
  • 4HARTWIG W,WERNER J,MULLER CA.Surgical management of severe pancreatitis including sterile necrosis[J].J Hepatobiliary Pancreat Surg,2002,9(4):429-435.
  • 5LUNA CM,VUJACICH P,NIEDERMAN MS,et al.Impact of BAL data on the therapy and outcome of ventilator associated pneumonia[J].Chest,1997,111(3):676-685.
  • 6HOERAUF A,HAMMER S,MILLER MYHSOK B,et al.Intraabdominal candida infection during acute necrotizing pancreatitis has a high prevalence and is associated with increased mortality[J].Crit Care Med,1998,26:201.
  • 7IBRAHIM EH,SHERMAN G,WARD S,et al.The influence of inadequate antimicrobial treatment of blood stream infections on patient outcomes in the ICU setting[J].Chest,2000,118(1):146-155.
  • 8HO HS,FREY CF.The role of antibiotic prophylaxis in severe acute pancreatitis[J].Arch Surg,1997,132(5):487-493.
  • 9HO HS,FREY CF.Gastrointestinal and pancreatic complications associated with severe pancreatitis[J].Arch Surg,1995,130(8):817-823.
  • 10BEGER HG,BITTNER R,BLOCK S,et al.Bacterial on tamination of pancreatic necrosis.A prospective clinical study[J].Gastroeoenterology,1986,91(2):433-438.

共引文献118

同被引文献57

引证文献12

二级引证文献72

;
使用帮助 返回顶部