青春期多囊卵巢综合征的诊治

The Diagnosis and Treatment of Polycystic Ovary Syndrome in Adolescent

由于青春期多囊卵巢综合征(PCOS)的病理变化与正常青春期生理变化相似,2012年提出青春期PCOS的诊断应同时符合Rotterdam标准的3个指标,即初潮后2年仍存在月经稀发或闭经、超声下多囊样卵巢(PCO)改变(包括卵巢体积>10 cm3)和高雄激素血症。尽管代谢因素不是PCOS的诊断指标,但仍应注意青春期PCOS患者代谢紊乱的发生情况。而青春期PCOS的治疗包括:生活方式调整,筛查并早期干预代谢紊乱,纠正月经周期紊乱。

Polycystic ovary syndrome（PCOS） is the most common endocrinopathy in women. PCOS often occurs in perimenarcheal girls, and similarities between the physiological changes of puberty and the pathological features of PCOS have been noted. The diagnosis of adolescent PCOS should simultaneously meet the three indexes of Rotterdam Consensus,hyperandrogenism as hyperandrogenemia（elevated blood androgens found using sensitive assays）,oligo-amenorrhea for at least 2 years after menarche, and polycystic ovaries also including increased ovarian volume （〉 10 cm^3）. Although metabolic syndrome is not included in the diagnosis of PCOS, metabolic condition in adolescent PCOS patients should be considered. Treatments of adolescent PCOS should include the modification of lifestyle and dietary ,improvement of metabolic disorders,and restoration of cyclical menses.