不同状态绝经后妇女激素替代疗法的个性化选择策略

Hormone Replacement Therapy should be Personalized

激素替代疗法(HRT)是目前缓解绝经相关症状和预防绝经后骨质疏松等疾病最有效的方案。HRT治疗中要求遵循个性化原则,根据患者的不同症状、年龄和不同的基础疾病状况,有无HRT适应证和禁忌证,掌握慎用情况及不同药物的特点,选择最佳治疗窗,使用最低剂量从而达到最佳治疗效果。

Hormone replacement therapy （HRT） is of choice for menopause population, to alleviate effectively those symptoms of menopause and to prevent the postmenopausal osteoporosis. However, it is necessary that HRT be personalized. The principles of personalized HRT are based on many aspects, such as symptoms, age, baseline diseases, indications and contraindications. When HRT is prescribed, many other aspects should be considered, including preparation and dose of HRT drug, route of administration, and the best ＇treatment window＇. The HRT should start at minimum dose with the best effect of treatment.