脑梗死后认知功能损害与神经功能恢复的相关性

Correlation of cognitive impairment and recovery of neural function in patients after cerebral infarction

目的探讨脑梗死后认知功能损害与神经功能恢复的相关性。方法 200例脑梗死患者入院时进行蒙特利尔认知评估量表(MoCA)测评,MoCA<26分者为认知功能损害(A组,162例),MoCA≥26分为无认知功能损害(B组,38例);入院时及治疗3个月后进行美国国立卫生院脑卒中量表(NIHSS)及日常生活活动能力Barthel指数(BI)测评。结果入院时及治疗后3个月时,A组NIHSS评分高于B组,BI低于B组(P<0.05);两组治疗后NIHSS均较入院时下降,BI升高(P<0.05),B组较A组更为明显(P<0.05)。治疗3个月后,MoCA评分与NIHSS评分呈负相关(r=-0.78,P<0.05),与BI评分呈正相关(r=0.51,P<0.05)。结论脑梗死后存在认知功能损害影响患者神经功能的恢复。

Objective To evaluate the correlation of cognitive impairment and recovery of neural function in the patients after cerebral infarction. Methods On the basis of scoring of Montreal cognitive assessment seale（MoCA） on admission, 200 patients with cerebral infarction were assigned into two groups of A（MoCA〈26 points, 162 cases with cognitive impairment） and B（MoCA≥26 points, 38 cases without cognitive impairment）. The US national institutes of health stroke scale （NIHSS） scores and ability of daily life activity Barthel index（BI） were evaluated on admission and 3 months after treatment. Results On admission and 3 months after treatment, the NIHSS score was lower,BI was higher, in group A than those in group B（P〈0. 05）. Compared to before, the NIHSS scores were reduced and BI increased 3 months after treatment in both groups（P〈0. 05）,which were more in group A than those in group B（P〈0. 05）. Three months after treatment, MoCA score was negatively correlated to NIHSS score （r=-0.78, P〈0. 05）, but positively correlated to BI （r= 0. 51, P〈0. 05）. Conclusion The presence of cognitive impairment affects the recovery of neurological function in the patients after cerebral infarction.