腺苷蛋氨酸治疗婴儿巨细胞病毒肝炎的临床疗效观察

Observation on Clinical Efficacy of Infant Cytomegalovirus Hepatitis with Adenosine Methionine

目的:观察腺苷蛋氨酸治疗婴儿巨细胞病毒性肝炎的临床疗效。方法:将82例婴儿巨细胞病毒性肝炎患儿采取随机双盲法分为治疗组46例和对照组36例,两组均给予更昔洛韦抗感染,茵栀黄退黄,对照组给予门冬氨酸钾镁保肝治疗,治疗组给予腺苷蛋氨酸保肝治疗,每组治疗10 d,每天一次。比较治疗前后两组肝功能各项指标的变化。结果:治疗前两组肝功能指标比较均无统计学差异(P>0.05);治疗后治疗组肝功能指标明显下降,较对照组有显著统计学差异(P<0.05)。结论:腺苷蛋氨酸治疗婴儿巨细胞病毒性肝炎安全有效,且不良反应少。

Objective： Observe the clinical curative effect of adenosine methionine treatment Infant Cy tomegalovirus Hepatitis. Methods ：82 cases Infant Cytomegalovirus Hepatitis were taken randomly divided into 46 cases of treatment group and control group 36 cases, two groups were given more wast, anti-infection, respectively. there Yin Zhi Huang, the control group given potassium magnesium protect liver treatment, treatment group given adenosine methionine protect liver treatment, 10 d, each treatment group once a day. Compare the change of two group＇s liver function indicators before and after the treatment. Results ：Treatment of liver function index to compare the first two group were no statistical differences （P〉0.05）; After treatment the treatment group significantly de creased liver function index, the control group had statistically significant difference （P〈0.05）. Conclusion ： Adeno sine methionine Infant Cytomegalovirus Hepatitis is safe and effective treatment, and less adverse reaction.