鞘内输注系统治疗顽固性癌痛

Applying intrathecal infusion system to treat intractable cancer pain

肿瘤患者疼痛的发生率较高,是临床尚未解决的难题。多项随机对照研究表明,鞘内输注镇痛药物是缓解癌痛的有效方法。鞘内药物输注系统在有效镇痛的同时,使不良反应最低。鞘内镇痛治疗使用越早患者受益越大。在给予体内植入鞘内给药装置前首先需要测试镇痛效果,恰当的实施测试时段极为重要,且有效维持时间决定患者是否适合接受植入鞘内镇痛系统。本文对鞘内药物输注系统的治疗依据、患者选择、测试、植入操作技术问题及并发症等方面进行阐述。

With a high incidence, cancer pain is an unresolved clinical problem right now. Many randomized controlled studies have shown that intrathecal infusion of analgesic drugs is an effective way to relieve pain. Intrathecal drug infusion system provides clinicians with exact individualized treatment approach in the effective analgesia, but with minimum side effects. Patients who received in trathecal analgesic therapy in the early stage would get more benefit. Before implanting intrathecal drug delivery devices, it is needed to test analgesic effect firstly, and the proper implementation of the test period is extremely important. This effectively maintaining time decides whether the patients need intrathecal analgesia system. However, there are many factors that may affect its application in clin ic. This article focuses on the treatment principle, patient selection, testing, technical problems and complications when applying intra thecal drug delivery devices.