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多精受精对胚胎发育及临床结局的影响 被引量:4

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摘要 目的了解体外受精-胚胎移植(in vitro fertilizati embryo transfer,IVF-ET)过程中多精受精对胚胎发育及妊娠结局的影响。方法回顾性分析在本中心2010-2012年IVF-ET治疗周期的资料,根据多精受精率分为3组:正常受精组,多精受精率为0;低频多精受精组,0<多精受精率≤25%;高频多精受精组,多精受精率>25%。共分析了1 144个IVF-ET周期的资料,其中正常受精组有593个周期,低频多精受精组有449个周期,高频多精受精组102个周期。比较各组的平均年龄、平均获卵数、成熟卵率、正常受精率(2PN)、正常受精卵裂率(2PN)、正常受精优胚率及临床妊娠率。结果除了正常受精卵裂率,3组的成熟卵率、正常受精率、正常受精优胚率、临床妊娠率均存在差异(P<0.05)。结论低水平多精受精率不影响临床妊娠率,高频多精受精不影响优胚率,但会降低临床妊娠率。
出处 《第三军医大学学报》 CAS CSCD 北大核心 2013年第19期2111-2112,共2页 Journal of Third Military Medical University
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