STAF评分在缺血性卒中患者心房颤动筛查的应用

The STAF score for screening atrial fibrillation in ischemic stroke

目的评价STAF评分(score for the targeting of atrial fibrillation,STAF)筛查缺血性卒中患者心房颤动(atrial fibrillation,AF)的诊断价值。方法为单中心、回顾性研究,连续收集年龄≥18岁、发病7 d内、经头颅MR/CT证实的缺血性卒中患者,收集其基本临床特征、入院首次美国国立卒中卫生院卒中评分量表(the Na tional Institute of Health stroke scale,NIHSS)评分、心脏彩超结果、经典TOAST(Trial of Org 10172 in Acute Stroke Treatment)分型、既往史、12导联心电图(electrocardiogram,ECG)、24小时动态心电图(24h-Holter)、心电监护结果并进行STAF评分。绘制受试者工作特征(receiver operator characteristic,ROC)曲线确定STAF诊断房颤的界值,分析其诊断价值。结果共收集患者219例,STAF评分诊断房颠的ROC曲线下面积(area under the curve,AUC)为0.901。以STAF≥5分作为界值,STAF评分的灵敏度为97.37%,特异度为70.72%。结论初步发现STAF评分对缺血性卒中患者具有较好的诊断价值,仍需进一步研究验证。

Objective To evaluate the sensitivity and specificity of the Score for the identification of Atrial Fi- brillation （STAF） in patients with isehemie stroke. Methods In this single center, retrospective study, patients aged 18 and older with CT or MRI confirmed isehemic stroke were consecutively admitted within 7 days after stroke onset The general clinical data, NIHSS score at admission, Eehocardiography, the TOAST classification, previous AF historic, 12 leads ECG result, 24-hours Holter result, and ECG monitoring result were collected to evaluate the STAF score. The STAF score was used to produce receiver operating characteristic （ROC） curve. Results A total of 219 adults with acute ischemic stroke were selected consecutively. The area under the ROC curve （AUC） of STAF was 0.901. The sen- sitivity and specificity of the STAF score were 97.37% and 70.72%, respectively. Conclusions The STAF score has a good diagnostic value for atrial fibrillation in isehemic stroke patients.