经颅直流电刺激在神经系统疾病中的应用研究进展

Advances on the application of transcranial direct current stimulation in the management of nervous system diseases

近年来神经系统疾病已经成为世界上死亡率、发病率、致残率较高的疾病。然而,如何更有效地治疗神经系统疾病,减少患者的痛苦及提高患者的生活质量已成为神经科学领域研究的热门话题。近来研究报道,经颅直流电刺激(transcranial direct current stimulation,tDCS)可通过微电流(阳极和阴极)刺激大脑兴奋以激活神经细胞活动并直接作用于大脑皮层引起皮质功能区的兴奋性增高,对各种神经系统疾病,如神经性头痛、脑卒中后的偏瘫、痉挛、失语症、帕金森病、抑郁症和认知功能障碍等疾病有一定的治疗作用。本研究结合近年已发表的研究成果对经颅直流电刺激与神经系统疾病的可能相关性作一综述。结果表明经颅直流电刺激能有效的促进中枢神经系统疾病患者的神经功能恢复。

In resent years the mortality, morbidity, and disability of nervous system diseases is high in the world. However, how to treat nervous systerm diseasea effectively, reduce the suffering of patients and improve the quality of their lives has become a hot topic in the field of neuroscience. It is proved that transcranial direct current stimulation （tDCS） may excite the brain to activate the activity of nerve cells and act directly on the brain cortex to elicite cortical functional area to increase its excitability by micro current （ anode and cathode ）. It is confirmed that tDCS has a certain therapeutic effec.on various nervous system diseases, such as nervous headache, hemiplegia after stroke, aphasia, spasm, Parkinson＇s disease, depression, cognitive dysfunction and other diseases. The progress of management of nervous system disease with tDCS are reviewed.