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磁共振扩散加权成像与动态增强磁共振成像在小儿肾积水肾功能评价中的应用 被引量:5

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摘要 目的 探讨磁共振扩散加权成像(DWI)和动态增强MRI在小儿肾积水肾功能评价中的应用价值.方法 对19例单侧肾积水患儿行MRI常规扫描、DWI和动态增强扫描,测量双侧肾脏的表观弥散系数(ADC)值,描绘肾脏皮质、髓质平均时间-信号强度曲线,记录皮质、髓质信号峰值,计算出肾脏通过时间(RTT),并对各参数进行相关性分析.将肾积水患儿的对侧正常肾脏作为正常对照组.结果 积水肾脏ADC值均显著低于正常对照组(P<0.01);积水肾脏与正常肾脏皮质信号峰值比较差异无统计学意义,积水肾脏髓质信号峰值较正常肾脏显著降低(P<0.01);RTT与ADC值呈负相关(r=-0.693,P<0.01),髓质信号峰值与ADC值呈正相关(r=0.762,P<0.01).结论 DWI和动态增强MRI可初步评估小儿肾积水肾功能改变.
作者 张岚 程敬亮
出处 《中华实用儿科临床杂志》 CAS CSCD 北大核心 2013年第17期1357-1358,共2页 Chinese Journal of Applied Clinical Pediatrics
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参考文献8

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